β 2 microglobulin also known as B2M is a component of MHC class I molecules, MHC class I molecules have α 1, α 2, and α 3 proteins which are present on all nucleated cells (excludes red blood cells).. In mielomul multiplu beta-2-microglobulina este cel mai valoros factor prognostic disponibil de rutina, fiind inclus in sistemul international de stadializare a acestei afectiuni. Niveluri crescute de beta-2-microglobulina constituie un marker predictiv pentru decesul precoce, precum si pentru esecul tratamentului cu doze mari.. Beta 2 microglobulina urinária Topic At a Glance What is being tested. B2M is frequently elevated in the blood with cancers such as multiple myeloma and lymphoma and with inflammatory disorders and infections e.. Beta-2 microglobulin (B2m) is the 11.8 kDa light-chain moiety of major histocompatibility complex class I (MHC I) present on the surface of nearly all nucleated cells MHC I functions immunologically in antigen presentation to cytotoxic T cells. Informatii generale. Beta 2 microglobulina (β 2-M) este o proteina cu masa moleculara de 11,8 kDa, ce constituie lantul usor al antigenelor complexului major de histocompatibilitate (HLA) clasa I, fiind, prin urmare, prezenta in membrana tuturor celulelor nucleate.. Beta-2 microglobulin (B2M) is a protein shed by cells into the blood, including tumor cells. The B2M test can be used as a tumor marker for some people with blood cell cancers (multiple myeloma, lymphoma) to give information about their likely prognosis..