Deoxyribonucleic acid (DNA) and ribonucleic acid (RNA) are essential biological molecules of life on Earth. Each and every living creature is using DNA as their genetic backbone. DNA can be found in cell nucleus in Eukaryotes, and it directs all cellular activity by allocating it to RNA. RNA has diverse biological roles in the human body such as in coding, decoding, regulation, and expression of genes. It transmits messages out of the cell nucleus to the cytoplasm. Ribose can be found in RNA, and it is an organic compound or precisely, a pentose monosaccharide. Deoxyribose is a monosaccharide that participates in the formation of DNA. It is a deoxy sugar that is derived from the sugar ribose by the loss of an oxygen atom. This is the main difference between Deoxyribose and Ribose. In this article, let’s elaborate the difference between ribose and deoxyribose in terms of their uses as well as chemical and physical properties.. beta-D-2-Deoxyribose | C5H10O4 | CID 439576 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities . D-2-deoxyribose is a precursor to the nucleic acid DNA. 2-deoxyribose is an aldopentose, that is, a monosaccharide with five carbon atoms and having an aldehyde functional group..