This test detects and measures one or more classes (IgG, IgM, or very rarely IgA) of beta-2 glycoprotein 1 antibodies. Beta-2 glycoprotein 1 antibody is a protein c-factro that binds to phospholipids.. Beta-2-Glycoprotein 1 (also known as apolipoprotein H), is a cofactor in antiphospholipid antibody binding and is the critical antigen in the antiphospholipid antibody syndrome. The presence of high titer IgG/IgM beta-2-glycoprotein 1 antibodies is one criteria for the diagnosis of antiphospholipid antibody syndrome.. Anti-beta-2-glycoprotein I antibody of IgG and/or IgM isotype in serum or plasma (in titer >the 99th percentile), present on two or more occasions at least 12 weeks apart APS is present if at least one of the clinical criteria and one of the laboratory criteria above are met. The presence of IgM antibodies to cardiolipin or beta-2-glycoprotein I at levels greater than 99th percentile is part . Beta-2 glycoprotein 1 (beta-2 GP1, also called apolipoprotein H) is a 326-amino acid polypeptide synthesized by hepatocytes, endothelial cells and trophoblast cells.. Beta-2 Glycoprotein-1 antibodies - IgG and IgM Indication. Suspected autoimmune arterial and / or venous thrombosis, thrombocytopenia, and repeated abortions.. Hi, I would be grateful if anyone can tell me how test results for Beta 2 Glycoprotein 1 Antibodies IgG and IgM are normally reported. I had a Beta 2 Glycoprotein 1 Antibodies IgG test and a Beta 2 Glycoprotein 1 Antibodies IgM test done as part of the Medichecks Hughes Syndrome Screening..