A medical examination will be necessary to determine if the body is suffering from an altered globulin ratio. Your doctor will perform a protein components test to measure the levels of albumin, alpha and beta globulin proteins. A small blood sample can be used to determine the levels of these proteins throughout the body, which will help your doctor determine if the ratios of proteins in your system is at a healthy level. Those who suffer from liver or kidney disorders will have these levels checked frequently to determine if their body is functioning safely. If there is a distinct alteration in your globulin levels, you will need to get medical attention right away to avoid doing serious damage to the body.. "2 Globulin Beta 1 Globulin Beta 2 Globulin Gamma Globulin M-Spike (or M protein , Monoclonal protein, etc.) The Beta 2 Glob you mention is probably the Beta 2 Globulin that is usually reported in these sorts of tests.. Ideally, albumin levels will fall at 4.5-5/100 ml, alpha globulin levels will remain at .2-.3 g/L and beta globulin levels will fall at .7-1.0 g/L. Low Globulin Levels. If the globulin levels fall below this normal range, it can be a sign of several serious health conditions..