BESPONSA is a type of medicine called an antibody-drug conjugate. BESPONSA is designed to find and attach to a specific protein, called CD22, found on leukemia cells BESPONSA is designed to find and attach to a specific protein, called CD22, found on leukemia cells. References. BESPONSA Prescribing Information. New York, NY: Pfizer Inc. Kantarjian HM, DeAngelo DJ, Stelljes M, et al. lnotuzumab ozogamicin versus standard therapy for acute lymphoblastic leukemia.. BESPONSA Prescribing Information Table 5. Laboratory Abnormalities in Patients with Relapsed or Refractory B-Cell Precursor ALL Who Received BESPONSA or Investigator’s Choice of Chemotherapy . 1 HIGHLIGHTS OF PRESCRIBING INFORMATION These highlights do not include all the information needed to use BESPONSA™ safely and effectively. See full prescribing information for. Besponsa reference guide for safe and effective use from the American Society of Health-System Pharmacists (AHFS DI).. Please click here to see full Prescribing Information, including BOXED WARNING, for BESPONSA. BESPONSA for injection is a white to off-white lyophilized powder supplied.