Prices and coupons for Besponsa. This prescription is provided by a doctor and is generally not available at a pharmacy. This drug is administered by your healthcare practitioner (HCP), which usually means: It may be expensive. You cannot fill this prescription in a regular pharmacy. Your doctor, hospital, or clinic will provide this medication. This drug is likely to be covered under your . “The approval of Besponsa is an important step forward for adult patients with relapsed or refractory B-cell acute lymphoblastic leukemia, a rare disease that can be fatal within a matter of . Cost-effectiveness of inotuzumab ozogamicin (Besponsa®) for the treatment of adults with relapsed or refractory CD22 positive B-cell precursor acute lymphoblastic leukaemia (ALL).. Pfizer criticized the National Institute of Health and Care Excellence for its decision that its new leukemia drug Besponsa was not cost effective.. Because of the “highly uncertain” survival benefits, the incremental cost effectiveness ratio (ICER) was over £100,000 per QALY for Besponsa, which is substantially higher than the range considered cost effective for routine use in the NHS.. BESPONSA is a type of medicine called an antibody-drug conjugate. BESPONSA is designed to find and attach to a specific protein, called CD22, found on leukemia cells BESPONSA is designed to find and attach to a specific protein, called CD22, found on leukemia cells.