BESPONSA can cause liver problems that can be severe, life-threatening, or fatal, including a condition called veno-occlusive disease (VOD). This condition can occur during treatment with BESPONSA or following subsequent treatment with a stem cell transplant. This condition was more common in patients who had elevated liver tests or who received dual alkylating agents in preparation for their stem cell transplant. Patients may be at a higher risk of VOD if they: . BESPONSA and MYLOTARG are available through a network of specialty distributors and one specialty pharmacy. SPECIALTY DISTRIBUTORS Please see full Prescribing Information for BESPONSA, including BOXED WARNING for hepatotoxicity, including VOD, and increased risk of post-HSCT non-relapse mortality, or visit BESPONSAhcp.com .. BESPONSA is a prescription medicine used to treat adults with relapsed or refractory B-cell acute lymphoblastic leukemia (ALL). It is not known if BESPONSA is safe and effective in children under 18 years of age..