42 termsjflockenTumor Markers-- AFP, beta-hCG, LDH, CEASTUDYPLAYTerms in this set (...)A tumor, either malignant or benign, is characterized by abnormal growth of tissue , without balanced cell death. T/FtrueWhich is a factor that affects cancer?a. location of originb. cell typec. stage at diagnosisd. resection abilitye. all of the aboveET/F a tumor marker is any kind of cellular signal that proves a patient has a specific cancer and where the cancer is located.false (a tumor marker is a tool that aids in the diagnosis, not necessarily where it is located specifically)Although tumor markers may help diagnose cancer, they are more frequently used fora. pointing out where a tumor isb. establishing a prognosis for the patientc. monitoring recurrence/response to treatmentd. deciding what stage of cancer the patient is inC (monitoring treatment is the more typical use)Alpha-feta protein (AFP) is elevated in what two cancers? (pick both letters)a. testicular CAb. melanomac. prostate CAd. Hepatocellular CA (HCC)a and d (testicular CA and HCC)AFP is used to screen men over 50 for testicular CA. T/Ffalse (not used for screening in testicular CA)Pt. has chronic liver disease, what test would you use to screen for HCC?AFP (only used for screening when pt is hgh risk, and has something like cirrhosis, hepatitis C or fibrosis)In a high risk patient, serum level of ____mcg/L of AFP is diagnostic for HCC>500 (mcg/L of AFP)Is HCC usually diagnosed early/late in disease?late (b/c liver has a large functional reserve)Clinical symptoms of HCC may include all of the following except:a. RUQ painb. Ascitesc. delayed satietyd. weight losse. obstructive jaundiceC (pts may have early satiety, especially if ascities or enlarged liver is taking up more of abdominal cavity)What kind of cancer is considered primary malignancy of the liver?HCC (hepatocellular carcinoma, vs the numerous other kinds of cancer that may spread to the liver)When pt. with HCC undergoes chemotherapy, AFP will only be increased if there is recurrence of HCC, T/F.false (may increase transiently while tumor cells lysed during first 25-30 days after chemo, and can have false-positives)The main utility of AFP is:a. screening patients with chronic liver disease for HCCb. screening all patients for HCC or testicular CAc. monitory response to treatment/detecting recurrence d. screening for appropriate increase immediately following chemoC (monitoring treatment)T/F serum AFP of >500 mcg/L is diagnostic of specific type of testicular cancerfalse (>10,000 mcg/L)what type of cancer is one of the most curable solid neoplasms, pt. may have elevated beta-hCG or AFP.testicular cancerTesticular cancers may arise from ____ cells?germWhat is the most commonly elevated tumor marker in testicular cancer?Beta-hCGbeta-hCGH has a (direct/inverse) relationship with tumor burden?direct (as tumor burden increases, more bHCG)due to the half life of bHCG being _____ days, there is (rapid/delayed) normalization after tumor removal?1.5-3 (days); rapid (normalization)if bHCG is elevated after orchiectomy this suggestsa. tumor has returnedb. tumor wasn't resected completelyc. there may be occult diseased. it wasn't testicular CA causing elevated levelsC (bHCG only associated with testicular CA, so if you remove tumor and still have levels this means the cancer likely spread somewhere else in the body)Which is not one of the three tests that work together to aid in dx of testicular CA, and help follow treatment?a. beta-hCGb. PSAc. LDHd. AFPB (PSA used for prostate cancer)LDH is only elevated in malignancy. T/Ffalse (elevated in almost any situation where there is tissue damage)_____% of men with testicular cancers have elevated LDH40-60(%)LDH has (low/high) specificitylow (lots of reasons it can be elevated)LDH has low sensitivity and specificity... so why is it used for testicular CA marker?a. it is only used with bHCG and AFP because only when all three are elevated is there diagnosisb. it is only used to help monitor after treatmentc. there are some cancers where it might be the only of the 3 markers elevatedd. it has high specificity for testicular CA, so it's actually the best markerC (there are some cases where its the only one elevated, can't take the chance to miss those markers so its included)in advanced germ cell tumors the degree of elevation of serum ____ has prognostic valueLDHWhat is the most commonly fatal form of skin cancer?melanomaWhat is the mnemonic for assessing skin for melanomasABCDE (asymmetry, border irregular, color variation, diameter more than 6mm, enlarged or color change)a serum ____ and a ____ x ray can serve as baseline for melanoma?LDH; chest (xray)if a melanoma is in transit pts have a >____% risk of systemic recurrence?50(%)LDH is a tumor marker for all of the following excepta. leukemia/lymphomab. testicular cancerc. melanomad. prostate cancerDLDH is associated with a plethora of lymphoma/leukemias because they are all characterized by increased ____ ____cell growth (and LDH is elevated during cell growth)What is the 3rd MC type of cancer, and 2nd most frequent cause of cancer-related death?colorectal cancer (CRC)T/F:the evolution of CRC is:non cancerous polyp --> cell growth --> cancerous tumor --> metastasis of cancerFalse (Starts with cell growth then forms a noncancerous polyp)Carcinoembrionic antigen (CEA) is specific for CRC? t/ffalse (lacks sensitivity and specificity)A patient presents with 2ng/mL of CEA... is this indicative of some type of CRC?no (normal values are 0-5 or 0-3)CEA is only used if pt has a mass viewed on colonoscopy which is confirmed to be colon cancer. T/Ftrue (only used one known dx)CEA (inversely/directly) correlates with disease burdendirectlyIf a patient has a pre-surgery CEA of 26 are they likely to have a better/worse/same outcome than a patient with a pre surgery CEA of 10... both patients CEA after surgery was 5worse (due to correlation with cancer burden the higher CEA likely will indicate a worse outcome)CEA may also be elevated in non-cancer-related states, including all of the following Except:a. gastritisb. liver diseasec. COPDd. PUDe. Gastric reflux diseaseEAfter confirmed diagnosis of CRC, CEA can be highly sensitive for detecting relapse. T/Ftrue (can be sensitive up to 60-90%)CEA can detect recurrence of CRC up to ___ months before detection by other means6YOU MIGHT ALSO LIKE...29 termsProstate Cancer67 termsSolid Malignancies/Cases75 termsALU 201, Chapter 3OTHER SETS BY THIS CREATOR17 termsEvaluation Forms46 termsGU Dysfunction (T2L4)23 termsSexual Assault (T1L2B)18 termsStatistical Inference for Categorical Data (test 3 ppt 2)THIS SET IS OFTEN IN FOLDERS WITH...21 terms2.1.4 Toxicology (salicylates, opioids, & cocaine overdoses)48 termsBlood Bank46 termsNeural Physiology-- resting membrane potential and graded potentials (*)25 termsPulmonary physical exam--ppt2FeaturesQuizlet LiveQuizlet LearnDiagramsFlashcardsMobileGCSEsHelpSign upHelp CenterHonor CodeCommunity GuidelinesStudentsTeachersAboutCompanyPressJobsAdvertisePrivacyTermsFollow usLanguageDeutschEnglish (UK)English (USA)EspañolFrançais (FR)Français (QC/CA)Bahasa IndonesiaItalianoNederlandspolskiPortuguês (BR)РусскийTürkçeTiếng Việt한국어中文 (简体)中文 (繁體)日本語© 2019 Quizlet Inc.. Hamilelikte düşük Beta HCG ne demektir? Uzman Tüp Bebek Doktoru Selim Şenöz Cevapladı. Tüp bebek ve Kadın Sağlığı ile ilgili bilgiler almak için web sitemizi ziyaret edebilirsiniz.. Beta HCG Hormonu Nedir? Beta HCG hormonu, hamile kaldıktan ne kadar süre sonra sonra kanda yükselmeye başlar? Beta HCG hormonu hakkında daha fazla bilgi için aşağıdaki linke .