Postmarketing reports: cataracts, , increased intraocular pressure, central serous chorioretinopathyMetabolicFrequency not reported: HyperglycemiaRenalFrequency not reported: GlucosuriaOtherRare (less than 0.1%): Rebound effectReferences1. Ruiz-Maldonado R, Zapata G, Lourdes T, Robles C "Cushing's syndrome after topical application of corticosteroids." Am J Dis Child 136 (1982): 274-52. "Product Information. Diprolene (betamethasone topical)." Schering Laboratories, Kenilworth, NJ. 3. Flynn MD, Beasley P, Tooke JE "Adrenal suppression with intranasal betamethasone drops." J Laryngol Otol 106 (1992): 827-84. Stevens DJ "Cushing's syndrome due to the abuse of betamethasone nasal drops." J Laryngol Otol 102 (1988): 219-215. Stoppoloni G, Prisco F, Santinelli R, Sicuranza G, Giordano C "Potential hazards of topical steroid therapy." Am J Dis Child 137 (1983): 1130-16. Reymann F, Kehlet H "Hypothalamic-pituitary-adrenocortical function. Association with topical application of betamethasone dipropionate." Arch Dermatol 115 (1979): 362-37. Cunliffe WJ, Burton JL, Holti G, Wright V "Hazards of steroid therapy in hepatic failure." Br J Dermatol 93 (1975): 183-58. Walsh P, Aeling JL, Huff L, Weston WL "Hypothalamus-pituitary-adrenal axis suppression by superpotent topical steroids." J Am Acad Dermatol 29 (1993): 501-39. Salde L, Lassus A "Systemic side-effects of three topical steroids in diseased skin." Curr Med Res Opin 8 (1983): 475-8010. Macdonald A "Topical corticosteroid preparations. Hazards and side-effects." Br J Clin Pract 25 (1971): 421-511. Smith EB, Breneman DL, Griffith RF, Hebert AA, Hickman JG, Maloney JM, Millikan LE, Sulica VI, Dromgoole SH, Sefton J, et al "Double-blind comparison of naftifine cream and clotrimazole/betamethasone dipropionate cream in the treatment of tinea pedis." J Am Acad Dermatol 26 (1992): 125-712. Grice K "Tinea of the hand and forearm. Betamethasone valerate atrophy." Proc R Soc Med 59 (1966): 254-513. Hellgren L "Induction of generalized pustular psoriasis by topical use of betamethasone-dipropionate ointment in psoriasis." Ann Clin Res 8 (1976): 317-914. Ellis CN, Katz HI, Rex IH Jr, Shavin JS, Van Scott EJ, VanderPloeg D "A controlled clinical trial of a new formulation of betamethasone dipropionate cream in once-daily treatment of psoriasis." Clin Ther 11 (1989): 768-7415. Sneddon I "Perioral dermatitis." Br J Dermatol 87 (1972): 430-416. Barkey WF "Striae and persistent tinea corporis related to prolonged use of betamethasone dipropionate 0.05% cream/clotrimazole 1% cream (Lotrisone cream)." J Am Acad Dermatol 17 (1987): 518-917. Eisenlohr JE "Glaucoma following the prolonged use of topical steroid medication to the eyelids." J Am Acad Dermatol 8 (1983): 878-8118. Butcher JM, Austin M, McGalliard J, Bourke RD "Bilateral cataracts and glaucoma induced by long term use of steroid eye drops." BMJ 309 (1994): 4319. Kitazawa Y "Increased intraocular pressure induced by corticosteroids." Am J Ophthalmol 82 (1976): 492-5Further informationAlways consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.. Along with its needed effects, betamethasone topical (the active ingredient contained in Betaderm) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.. Betaderm pharmaceutical active ingredients containing related brand and generic drugs: Active ingredient is the part of the drug or medicine which is biologically active. This portion of the drug is responsible for the main action of the drug which is intended to cure or reduce the symptom or disease..