Other names for this marker: – β 2-Glycoprotein 1 Antibodies, IgA – Beta-2 Glycoprotein 1 Antibodies, IgA – Beta-2 Glycoprotein 1 Antibodies, IgA, Serum. The antiphospholipid syndrome (APS) is a systemic autoimmune disorder characterized by the main clinical features of venous and/or arterial thrombosis (intravascular blood clotting), thrombocytopenia, recurrent fetal loss, and moderate-to-high titers of antiphospholipid (aPL) antibodies, lupus anticoagulant, anti-cardiolipin antibodies . The persistent presence of IgG and/or IgM beta 2 glycoprotein I (B2GPI) antibodies (greater than 99th percentile) is a laboratory criterion for the diagnosis of antiphospholipid syndrome (APS).. Test Name Beta-2-Glycoprotein I Antibodies, IgG, IgM & IgA Test Code 2496 CPT Code(s) 86146 x3 Preferred Requirement(s) Serum Transport Temperature Refrigerated Methodology Multiplex Flow Immunoassay Days Performed See individual test for details.. Beta-2-Glycoprotein 1 (also known as apolipoprotein H), is a cofactor in antiphospholipid antibody binding and is the critical antigen in the antiphospholipid antibody syndrome. The presence of high titer IgG/IgM beta-2-glycoprotein 1 antibodies is one criteria for the diagnosis of antiphospholipid antibody syndrome.. Collection Guide. Specimen processing is one of the most important aspects in the generation of accurate and reliable lab results. Many variables, such as, anticoagulant ratio, storage time and temperature, and surface of containers and drawing components can affect test results..